Brand Name: SB-Dom 10
Generic Name: Domperidone Maleate BP
Strength: 10 mg
SB-Dom 10 Tablet: Each film coated tablet contains Domperidone Maleate BP equivalent to Domperidone 10 mg.
SB-Dom is indicated in-
- Stimulation of gut motility
- a) Non-ulcer dyspepsia
- b) Esophageal reflux, reflux esophagitis and gastritis
- c) Diabetic gastroparesis
- d) Functional dyspepsia
- e) Speeding Barium transit in ‘follow-through’ radiological studies
- Prevention and symptomatic relief of acute nausea and vomiting from any cause including cytotoxic therapy, radio therapy and anti-parkinsonism therapy
- In the treatment of migraine.
Dosage & Administration
The recommended oral dose for
Adults : 10 – 20 mg every 4 – 8 hours daily.
Children : 0.2 – 0.4 mg/kg every 4 – 8 hours daily.
Note : Tablet and suspension should be taken 15 – 30 minutes before a meal.
For acute nausea and vomiting, maximum period of treatment is 12 weeks.
Domperidone may produce hyperprolactinemia (1.3% frequency). This may result in galactorrhea, breast enlargement and soreness and reduced libido. Dry mouth (1.9%), thirst, headache (1.2%), nervousness, drowsiness (0.4%), diarrhea (0.2%), skin rash and itching (0.1%) may occur during treatment with Domperidone. Extra-pyramidal reactions are seen in 0.05% of patients in clinical studies.
Domperidone is contraindicated to patients who have known hypersensitivity to this drug and in case of neonates.
Use in Pregnancy & Lactation
Pregnant women : The safety of Domperidone has not been proven and it is therefore not recommended during pregnancy.Animal studies have not demonstrated teratogenic effects on the fetus.
Lactating mother : Domperidone may precipitate galactorrhea and improve post-natal lactation. It is secreted in breast milk but in very small quantities (insufficient to be considered harmful).
SB-Dom 10 Tablet : Each box contains 100 film coated tablets in blister pack.